Claudia Hortensia is the deceased wife of Kirei Kotomine and mother of Caren Hortensia. Claudia was an albino and immune deficient, making it so that she could die from even a tiny wound. Her body always appeared tattered as a result. Caren inherited the aspect of "prone to be plagued by illnesses." Kirei thinks of Claudia as a saint, understanding his anger and remaining faithful in trying to save him. He believes nobody will ever understand him to such a degree as her.
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