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Dio Brando, known simply as DIO from Part 3 onwards, is the main antagonist of both Phantom Blood and Stardust Crusaders. However, his influence is felt through all of the first six parts of the series up to Stone Ocean, with major characters such as Giorno Giovanna or Enrico Pucci being directly connected to him. Originally a man of low birth but peerless ambition, Dio is a villain of little conscience, vast cunning, and an insatiable hunger for power. After becoming a vampire and later a Stand user, Dio has gathered around him many minions and is responsible for many major events, and his legacy persists throughout the series.

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