Kanna Ōtsutsuki was a villager during the era of Ninshū, where she lived in a village that Asura Ōtsutsuki was tasked to help. She eventually grew closer to him and became his wife. Kanna lived in a village whose people were suffering from a strange illness that her mother fell victim to. When Asura and Taizō came to the village to solve their "problem" that Hagoromo Ōtsutsuki had tasked them with solving, she believed they were bandits where she was injured in the scuffle but Asura healed her gaining her trust. Seeing his healing abilities she hoped Asura could save her ailing mother but learned that the God Tree's influence was keeping her sick. When they confronted the elder about this, he revealed because there was nothing that could be done and she was forced to show Asura away.