Kuumi

Kuumi is an artificial kannagi, a being gifted with uncontrollable magical powers. Having fled from a research facility, she meets Myaa, a young girl with a cat headdress, and Jiiro, a nagimori (champions who utilize the destructive power of a kannagi to defeat giant monsters). The trio starts traveling together to protect Kuumi from the underlings of Mezami, the head of the research facility. Kuumi's name comes from her serial number (22).