Natsumi Kuzuryu is the younger sister of Fuyuhiko Kuzuryu and a Hope's Peak Academy Reserve Course Student. She is a key subject in the Twilight Syndrome Murder Case featured in Danganronpa 2: Goodbye Despair and later featured in Danganronpa 3: The End of Hope's Peak High School. Natsumi had demonstrated extreme egotism and smugness upon her introduction to the rest of the Reserve Course students. In Twilight Syndrome Murder Case and according to Girl E, Natsumi was described as a mean and egotistical girl who would plant hatred towards someone she dislikes or envy. Natsumi is also said by her parents to be much more violent than her brother and more worthy of being the Yakuza heiress.