Taking place in a futuristic city called Kamina City, Rune Balot is a prostitute who was taken in by the notorious gambler Shell Septinous. One night, Shell abandons Rune and attempts to murder her in an explosion. However, she is rescued and transformed into a cyborg by Dr. Easter under regulation Mardock Scramble 09, an emergency ordinance where experimental technologies can be used to preserve life
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