Tsunade (綱手) is a descendant of the Senju clan and one of Konohagakure's Sannin; famed as the world's strongest kunoichi and its greatest medical-nin. The repeated loss of her loved ones caused Tsunade to develop a crippling fear of blood and she would later abandon the life of a shinobi for many years. She is eventually persuaded to return to Konoha and take on the mantle of Fifth Hokage, where her skills prove invaluable to the village. Tsunade was very willing to believe in the attainability of dreams while Nawaki and Dan were alive, and that by supporting and encouraging those dreams she might be able to help achieve them. When both died gruesomely shortly after receiving her support, Tsunade lost faith in the idea of dreaming for anything, believing that the mere pursuit would be doomed from the outset. She becomes especially critical of wanting to be Hokage, as both Dan and Nawaki died trying to attain the title and the past Hokage have all died prematurely and, Tsunade argues, pointlessly because they held the position; she concludes that to be Hokage is a fool's job. Tsunade has brown eyes and straight, shoulder-length blonde hair that she usually keeps tied in two loose ponytails. The Strength of a Hundred Seal - taking the appearance of a violet diamond shape - is clearly visible on her forehead. Although she was called flat-chested when she was younger, Tsunade has large breasts, which Jiraiya estimates to be 106 centimetres in circumference; she is in fact widely regarded as the most beautiful kunoichi in the world. Despite being in her fifties, Tsunade maintains the appearance of a young woman using the Transformation Technique. She has not been shown in full when not transformed, but what little of her body that is seen is heavily wrinkled and frail. Tsunade often wears a grass-green haori with the kanji for "gamble" written on the back, inside a red circle. Underneath she wears a grey, kimono-style blouse with no sleeves, held closed by a broad, dark bluish-grey obi that matches her pants. Her blouse is closed quite low, revealing her sizeable cleavage. She wears open-toed, strappy black sandals with high heels. She has red polish on both her fingernails and toenails and uses a soft pink lipstick. She wears the First Hokage's necklace for many years until she gives it to Naruto.